FPR2 anticorps (AA 181-192)

N° du produit ABIN452644

Cet anticorps Souris Monoclonal détecte spécifiquement FPR2 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour FPR2 anticorps (AA 181-192) (ABIN452644)

Antigène: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FPR2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: C4F9

Détail du produit anti-FPR2 anticorps

Épitope: AA 181-192

Specificité: This monoclonal antibody reacts with the above mentioned peptide in ELISA and reacts with the 38KDa FPRL1 on Western Bloton.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: N-formyl peptide receptor 2, FMLP-R-I, FPRH1, RFP, LXA4R, FMLP-related receptor I, Formylpeptide receptor-like 1, Lipoxin A4 receptor

Purification: Affinity Chromatography.

Immunogène: A short KLH conjugated peptide corresponding to the amino acid sequence 181-192(ASWGGTPEERLK) on Human FPRL1

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot (1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur FPR2

Antigène: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Autre désignation: FPR2 / FPRL1

Sujet: Human formyl peptide receptor-like 1(FPRL1) is a G-protein coupled seven transmembrane receptor. The receptor can bind to the formyl peptides derived from the degradation of the cell wall of infected bacteria and host cells. FPRL1 expressed on the cell surface of neutrophils and other leukocytes mediates the chemotaxis of these cells toward infected site. It has been reported that acute phase protein SAA is also a ligand of FPRL1 and SAA can induce the secretion of IL-8 and TNF-α by neutrophil through FPRL1 signalling. FPRL1 has also been shown to mediate the chemotaxis of microglia by Abeta42 peptide and the internalization of Abeta42 peptide into cytoplasma of macrophage, indicating that FRPL1 may participate in the Abeta42 peptide elicited pathogenesis in Alzheimer's disease.Synonyms: FMLP-R-I, FMLP-related receptor I, FPRH1, Formyl peptide receptor-like 1, LXA4R, Lipoxin A4 receptor, N-formyl peptide receptor 2, RFP

ID gène: 2358

UniProt: P25090